Relevant publications

Selected journal publications


Respiratory

J.H. Naish, G.J.M. Parker, P.C. Beatty, A. Jackson, J.C. Waterton, S.S. Young, C.J. Taylor. Improved quantitative dynamic regional oxygen-enhanced pulmonary imaging using image registration. Magn. Reson. Med. 54(2), 464-469, (2005).

J.N. Naish, L.E. Kershaw, D.L. Buckley, A. Jackson, J.C. Waterton, G.J.M. Parker. Modelling of contrast agent kinetics in the lung using T1-weighted dynamic contrast-enhanced MRI. Magn. Reson. Med. 61(6), 1507-1514, (2009).

M.G. Crabb, J.L. Davidson, R. Little, P. Wright, A.R. Morgan, C.A. Miller, J.H. Naish, G.J.M. Parker, R. Kikinis, H. McCann, W.R.B. Lionheart. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Physiol. Meas. 35, 863-876, (2014). doi: 10.1088/0967-3334/35/5/863

A.R. Morgan, G.J.M. Parker, C. Roberts, G.A. Buonaccorsi, N.C. Maguire, P.L. Hubbard Cristinacce, D. Singh, J. Vestbo, L. Bjermer, J. Jögli, Z. Taib, J. Sarv, P.L.B. Bruijnzeel, L.E. Olsson, E. Bondesson, U. Nihlen, D.M. McGrath, S.S. Young, J.C. Waterton, L.H. Nordenmark. Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD. Eur. J. Radiol. 38, 2093-2101, (2014). doi: 10.1016/j.ejrad.2014.08.004

W.-J. Zhang, R.M. Niven, S.S. Young, Y.-Z. Liud, G.J.M. Parker, J.H. Naish. Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma—Initial experience. Eur. J. Radiol. 84(2), 318-326, (2015). doi: 10.1016/j.ejrad.2014.10.021.

W.-J. Zhang, P.L. Hubbard Cristinacce, E. Bondesson, L.H. Nordenmark, S.S. Young, Y.-Z. Liu, D. Singh, J.H. Naish, G.J.M. Parker. MR quantitative equilibrium signal mapping: a reliable alternative to CT for the assessment of emphysema in COPD. Radiology. 275(2), 579-588, (2015). doi: 10.1148/radiol.14132953

H.A.W.M. Tiddens, S.M. Stick, J.M. Wild, P. Ciet, G.J.M. Parker, A. Koch, J. Vogel-Claussen. Respiratory tract exacerbations revisited: Ventilation, Inflammation, Perfusion, and Structure (VIPS) monitoring to redefine treatment. Ped. Pulmonol. 50, S57-S65, (2015). doi: 10.1002/ppul.23266

D.F. Alamidi, S.S.I. Kindvall, P.L. Hubbard Cristinacce, D.M. McGrath, S.S. Young, J.H. Naish, J.C. Waterton, P. Woollmer, S. Diaz, M. Olsson, P.D. Hockings, K.M. Lagerstrand, G.J.M. Parker, L.E. Olsson. T1 Relaxation Time in Lungs of Asymptomatic Smokers. PLoS ONE 11(3), (2016). doi: doi.org/10.1371/journal.pone.0149760

W.-J.Zhang, R.M. Niven, S.S. Young, Y.-Z. Liu, G.J.M. Parker, J.H. Naish. T1-weighted Dynamic Contrast-enhanced MR Imaging of the Lung in Asthma: Semiquantitative Analysis for the Assessment of Contrast Agent Kinetic Characteristics. Radiology 278(3), 906-916 (2016). doi: 10.1148/radiol.2015141876

D.F. Alamidi, A.R. Morgan, P.L. Hubbard Cristinacce, L.H. Nordenmark, P.D. Hockings, K.M. Lagerstrand, S.S. Young, J.H. Naish, J.C. Waterton, N.C. Maguire, L.E. Olsson, G.J.M. Parker. COPD patients have short lung magnetic resonance T1 relaxation time. COPD: J Chronic Obstructuve Pulmonary Disease 13(2). 153-159, (2016). doi:10.3109/15412555.2015.1048851 


Oncology

G.C. Jayson, G.J.M. Parker, S. Mullamitha, J.W. Valle, M. Sunders, L. Broughton, J. Lawrence, B. Carrington, C. Roberts, B. Issa, D.L. Buckley, S. Cheung, K. Davies, Y. Watson, K. Zinkewich-Péotti, L. Rolfe, A. Jackson. Blockade of PDGF receptor beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularised volume. J. Clin. Oncol. 23, 973-981, (2005).

J.P. O’Connor, G.C. Jayson, A. Jackson, D. Ghiorghiu, B.M. Carrington, C.J. Rose, S.J. Mills, R. Swindell, C. Roberts, C.L. Mitchell, G.J.M. Parker. Enhancing fraction predicts clinical outcome following first line chemotherapy in patients with epithelial ovarian carcinoma. Clin. Cancer Res. 31(20): 6130-6135, (2007).

S. Mullamitha, C. Ton, G.J.M. Parker, A. Jackson, P.J. Julyan, C. Roberts, G.A. Buonaccorsi, L. Broughton, J.W. Valle, J.A. Radford, M.C. Munteanu, M.T. Nakada, J.A. Nemeth, H.M. Davis, Q. Jiao, U. Prabhakar, Z. Lang, R.E. Corringham, R.A. Beckman, G.C. Jayson. Phase I evaluation of a fully human anti-αv integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors. Clin. Cancer Res. 13(7), 2128-2135, (2007). 

N.C. Ton, G.J. Parker, A. Jackson, S. Mullamitha, G.A. Buonaccorsi, C. Roberts, Y. Watson, K. Davies, S. Cheung, L. Hope, F. Power, J. Lawrance, J. Valle, M. Saunders, R. Felix, J.A. Soranson, L. Rolfe, K. Zinkewich-Peotti, G.C. Jayson. Phase I Evaluation of CDP791, a PEGylated Di-Fab' Conjugate that Binds Vascular Endothelial Growth Factor Receptor 2. Clin. Cancer Res. 13(23): 7113-7118, (2007).

J.P.B. O’Connor, J.H. Naish, G.J. M. Parker, J.C. Waterton, Y. Watson, G.C. Jayson, Ph.D., G.A. Buonaccorsi, S. Cheung, D.L. Buckley, D.M. Mcgrath, C.M.L. West, S.E. Davidson, C. Roberts, S.J. Mills, C.L. Mitchell, L. Hope,  N.C. Ton,  A Jackson. Preliminary study of oxygen-enhanced longitudinal relaxation In MRI: A potential novel biomarker of oxygenation changes in solid tumors. Int. J. Radiat. Oncol. Biol. Phys. 75(4), 1209-1215, (2009).

J.B.P. O’Connor, R.A.D. Carano, A.R. Clamp, J. Ross, C.C.K. Ho, A. Jackson, G.J.M. Parker, C.J. Rose, F.V. Peale, M. Friesenhahn, C.L. Mitchell, Y. Watson, C. Roberts, L. Hope, S. Cheung, H.B. Reslan, M.A.T. Go, G.J. Pacheco, X. Wu, T.C. Cao, S. Ross, G.A. Buonaccorsi, K. Davies, J. Hasan, P. Thornton, O. del Puerto, N. Ferrara, N. van Bruggen, G.C. Jayson. Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor. Clin. Cancer. Res. 15(21), 6674-6682, (2009). 

C.L. Mitchell, J.P. O'Connor, A. Jackson, G.J. Parker, C. Roberts, Y. Watson, S. Cheung, K. Davies, G.A. Buonaccorsi, A.R. Clamp, J. Hasan, L. Byrd, A. Backen, C. Dive, G.C. Jayson. Identification of early predictive imaging biomarkers and their relationship to serological angiogenic markers in patients with ovarian cancer with residual disease following cytotoxic therapy. Ann. Oncol. 21(10), 1982-1989, (2010).

J.P.B. O’Connor, C.J. Rose, A. Jackson, Y. Watson, S. Cheung, G.C. Jayson, F. Maders, B.J. Whitcher, C. Roberts, G.A. Buonaccorsi, G. Thompson, G.J.M. Parker. DCE-MRI biomarkers of microvascular structure and function predict CRC liver metastasis shrinkage induced by bevacizumab and FOLFOX-6. Brit. J. cancer. 105, 139-145, (2011).

C.L. Mitchell, J.P.B. O’Connor, C. Roberts, Y. Watson, A. Jackson, S. Cheung, J. Evans, J. Spicer, A. Harris, C. Kelly, S. Rudman, M. Middleton, A. Fielding, J. Tessier, H. Young, G.J.M. Parker, G.C. Jayson. A two-part Phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics. Cancer Chemother. Pharmacol. 68(3), 631–641, (2011). doi: 10.1007/s00280-010-1534-3

A. Banerji, J.H. Naish, Y. Watson, G.C. Jayson, G.A. Buonaccorsi, G.J.M. Parker. DCE-MRI model selection for investigating disruption of microvascular function in livers with metastatic disease. J. Magn. Reson. Imag. 35(1), 196-203, (2012).

M.O. Leach, B. Morgan, P.S. Tofts, D.L. Buckley, W. Huang, M.A. Horsfield, T.L. Chenevert, D.J. Collins, A. Jackson, D. Lomas, B. Whitcher, L. Clarke, R. Plummer, I. Judson, R. Jones, R. Alonzi, T. Brunner, D.M. Koh, P. Murphy, J.C. Waterton, G. Parker, M.J. Graves, T.W.J. Scheenen. T.W. Redpath. M. Orton, G. Karczmar, H. Huisman, J. Barentsz, A. Padhani, on behalf of the Experimental Cancer Medicine Centres Imaging Network Steering Committee. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. Eur. Radiol. 22, 1451-1464, (2012).

I.V. Linnik, M.L.J. Scott, K. Holliday, N. Woodhouse, J.C. Waterton, J.P.B. O’Connor, H. Barjat, C. Liess, J. Ulloa, H. Young, C. Dive, C.L. Hodgkinson, T. Ward, D. Roberts, S.J. Mills, G. Thompson, G.A. Buonaccorsi, S. Cheung, A. Jackson, J.H. Naish, G.J.M. Parker. Non-invasive tumor hypoxia measurement using magnetic resonance imaging in mouse and human glioblastoma. Magn. Reson. Med. 71(5), (2014). doi: 10.1002/mrm.24826

G.Z. Ferl, J.P.B. O'Connor, G.J.M. Parker, R.A.D. Carano, S.J. Acharya, G.C. Jayson, R.E. Port. Mixed-effects modeling of clinical DCE-MRI data: Application to colorectal liver metastases treated with bevacizumab. J. Magn. Reson. Imag. 41(1), 132–141, (2015). doi: 10.1002/jmri.2451

Y. Jamin, J.K.R. Boult, J. Li, S. Popov, P. Garteiser, J.L. Ulloa, C. Cummings, G. Box, S.A. Eccles, C. Jones, J.C. Waterton, J.C. Bamber, R. Sinkus, S.P. Robinson. Exploring the biomechanical properties of brain malignancies and their pathological determinants in vivo with magnetic resonance elastography. Cancer Research 75(7), 1216-24, (2015) doi: 10.1158/0008-5472.CAN-14-1997

J.P.B. O’Connor, J.K. Boult, Y. Jamin, M. Babur, K.G. Finegan, K.J. Williams, R.A. Little, A. Jackson, G.J.M.Parker, A.R. Reynolds, J.C. Waterton, S.P. Robinson. Oxygen enhanced MRI accurately identifies, quantifies, and maps hypoxia in preclinical cancer models. Cancer Research  76, 787-795, (2016). doi: 10.1158/0008-5472.CAN-15-2062, Front cover plus editorial.

S.J. Mills, D. du Plessis, P. Pal, G. Thompson, G. Buonaccorsi, C. Soh, G.J.M. Parker, A. Jackson. Mitotic Activity in Glioblastoma Correlates with Estimated Extravascular Extracellular Space Derived from Dynamic Contrast-Enhanced MR Imaging. AJNR American Journal of Neuroradiology AJNR American Journal of Neuroradiology 37(5), 811-817, (2016). doi: 10.3174/ajnr.A4623

J.P.B. O’Connor, E.O. Aboagye, J.E. Adams, H.J.W.L. Aerts, S.F. Barrington, A.J. Beer, R. Boellaard, S.E. Bohndiek, M. Brady, G. Brown, D.L. Buckley, T.L. Chenevert, L.P. Clarke, S. Collette , G.J. Cook, N.M. deSouza, J.C. Dickson, C. Dive, J.L. Evelhoch, C. Faivre-Finn, F.A. Gallagher, F.J. Gilbert, R.J. Gillies, V. Goh, J.R. Griffiths, A.M. Groves, S. Halligan, A.L. Harris, D.J. Hawkes, O.S. Hoekstra, E.P. Huang, B.F. Hutton, E.F. Jackson, G.C. Jayson, A. Jones, D.-M. Koh, D. Lacombe, P. Lambin, N. Lassau, M.O. Leach, T.-Y. Lee, E.L. Leen, J.S. Lewis, Y Liu, M.F. Lythgoe, P. Manoharan, R.J. Maxwell, K.A. Miles, B. Morgan, S. Morris, T. Ng, A.R. Padhani, G.J.M. Parker, M. Partridge, A.P. Pathak, A.C. Peet, S. Punwani, A.R. Reynolds, S.P. Robinson, L.K. Shankar, R.A. Sharma, D. Soloviev, S. Stroobants, D.C. Sullivan, S.A. Taylor, P.S. Tofts, G.M. Tozer, M. van Herk, S. Walker-Samuel, J. Wason, K.J. Williams, P. Workman, T.E. Yankeelov, K.M. Brindle, L. M. McShane, A. Jackson, J.C. Waterton. Imaging biomarker roadmap for cancer studies. Nat. Rev. Clin. Oncol. (In press). http://doi.org/10.1038/nrclinonc.2016.162


Neuroscience

M. Bozzali, G.J.M. Parker, L. Serra, K. Embleton, T. Gill, R. Perri, C. Caltagirone, M. Cercignani. Anatomical connectivity mapping: A new tool to assess brain disconnection in Alzheimer's disease. NeuroImage, 54(3), 2045-2051, (2011). doi:10.1016/j.neuroimage.2010.08.069

M. Cercignani, K. Embleton, G.J.M. Parker, M. Bozzali. Group-averaged anatomical connectivity mapping for improved human white matter pathway visualisation. NMR in Biomed. 25(11), 1224-1233, (2012). doi:10.1002/nbm.2793

M. Bozzali, B. Spano, G. Parker, G. Giuletti, M. Castelli, B. Basile, S. Rossi, L. Serra, G. Magnani, U. Nocentini, C. Caltagrione, D. Centonze, M. Cercignani. Anatomical brain connectivity can assess cognitive dysfunction in multiple sclerosis. Multiple Sclerosis Journal 19(9), 1161-1168, (2013). doi: 10.1177/1352458512474088

M. Bozzali, G.J.M. Parker, B. Spano, L. serra, G. Giulietti, R. Perri, G. Magnani, C. Marra, M.G. Vita, C. Caltagirone, M. Cercignani. Brain tissue modifications induced by cholinergic therapy in Alzheimer’s disease. Human Brain Mapping 34(12), 3158-3167, (2013). doi: 10.1002/hbm.22130

Y. Assaf, D.C. Alexander, D.K. Jones, A. Bizzi, T.E.J. Behrens, C.A. Clark, Y. Cohen, T.B. Dyrby, P.S. Huppi, T.R. Knoesche, D. Le Bihan, G.J.M. Parker. The CONNECT project: Combining macro- and micro-structure. NeuroImage 80, 273-282, (2013). doi: 10.1016/j.neuroimage.2013.05.055.

M. Lyksborg, H.R. Siebner, P.S. Sørensen, M. Blinkenberg, G.J.M. Parker, A.-M. Dogonowski, E. Garde, R. Larsen, T.B. Dyrby. Secondary Progressive and Relapsing Remitting Multiple Sclerosis Leads to Motor-Related Decreased Anatomical Connectivity. PLoS ONE 9(4): e95540, (2014). doi:10.1371/journal.pone.0095540

N. Muhlert, V. Sethi, L. Cipolotti, H. Haroon, G.J.M. Parker, T. Yousry, C. Wheeler-Kingshott, D. Miller, M. Ron, D. Chard. The grey matter correlates of impaired decision-making in multiple sclerosis. JNNP 86(5), 530-536 (2015). doi: 10.1136/jnnp-2014-308169

C.J. Bajada, H.A. Haroon, H. Azadbakht, G.J.M. Parker, M.A. Lambon Ralph, L.L. Cloutman. The Tract Terminations in the Temporal Lobe: Their location and associated functions. Cortex. (In press). doi: 10.1016/j.cortex.2016.03.013

C.J. Bajada, R.L Jackson, H.A. Haroon, H. Azadbakht, G.J.M. Parker, M.A. Lambon Ralph, L.L. Cloutman. A graded tratographic parcellation of the temporal lobe. NeuroImage. (In press). doi: 10.1016/j.neuroimage.2017.04.016


Methods-focussed

G.J.M. Parker, C. Roberts, A. Macdonald, G.A. Buonaccorsi, S. Cheung, D.L. Buckley, A. Jackson, Y. Watson, K. Davies, G.C. Jayson. An experimentally-derived functional form for a population-averaged high temporal resolution arterial input function for dynamic contrast-enhanced MRI. Magn. Reson. Med. 56, 993-1000, (2006).

C. Roberts, B. Issa, A. Stone, A. Jackson, J.C. Waterton, G.J.M. Parker. Comparative study into the robustness of compartmental modelling and model-free analysis in DCE-MRI studies. J. Magn. Reson. Imag. 23, 544-563, (2006).

C. Roberts, D.L. Buckley, G.J.M. Parker. Comparison of errors associated with single and multi-bolus injection protocols in low temporal resolution dynamic contrast enhanced tracer kinetic analysis. Magn. Reson. Med. 56, 611-619, (2006).

G.A. Buonaccorsi, C. Roberts, S. Cheung, Y. Watson, J. O’Connor, K. Davies, A. Jackson, G.C. Jayson, G.J.M. Parker. Comparison of the performance of tracer kinetic model-driven registration for dynamic contrast enhanced MRI (DCE-MRI) using different models of contrast enhancement. Acad. Radiol. 13, 1112-1123, (2006).

J.P.B. O’Connor, A. Jackson, G.A. Buonaccorsi, Y. Watson, S. Cheung, C. Roberts, D.M. McGrath, C. Rose, P.M. Dark, G.C. Jayson, D.L. Buckley, G.J.M. Parker. Organ-specific effects of oxygen and carbogen gas inhalation on tissue longitudinal relaxation times. Magn. Reson. Med. 58, 490-496, (2007). 

G.A. Buonaccorsi, J.P.B. O’Connor, A. Caunce, C. Roberts, S. Cheung, Y. Watson, K. Davies, A. Jackson, G.C. Jayson, G.J.M. Parker. Tracer kinetic model driven registration for DCE-MRI time-series data. Magn. Reson. Med. 58: 1010-1019, (2007).

D.M. McGrath, J.H. Naish, J.P.B. O’Connor, C.E. Hutchinson, J.C. Waterton, C.J. Taylor, G.J.M. Parker. Oxygen-induced changes in longitudinal relaxation times in skeletal muscle. Magn. Reson. Imag. 26: 221-227, (2008).

J.B.P. O'Connor, J.H. Naish, A. Jackson, J.C. Waterton, Y. Watson, S. Cheung, D.L. Buckley, D.M. McGrath, G.A. Buonaccorsi, S.J. Mills, C. Roberts, G.C. Jayson, G.J.M. Parker. Comparison of normal tissue R1 and R2* modulation by oxygen and carbogen. Magn. Reson. Med. 61, 75-83, (2009).

C.J. Rose, S.J. Mills, J.P.B. O’Connor, G.A. Buonaccorsi, C. Roberts, S. Cheung, S. Zhao, B. Whitcher, G.J.M. Parker. Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magn. Reson. Med. 62, 488-499, (2009).

C. Roberts, R. Little, Y. Watson, S. Zhao, D.L. Buckley, G.J.M. Parker. The effect of blood inflow and B1-field inhomogeneity on measurement of the arterial input function in axial 3D spoiled gradient echo dynamic contrast-enhanced MRI. Magn. Reson. Med. 65(1), 108-119, (2011). doi: 10.1002/mrm.22593

C.J. Rose, J.P.B. O'Connor, T.F. Cootes, C.J. Taylor, G.C. Jayson, G.J.M. Parker, J.C. Waterton. Indexed distribution analysis significance improved significance testing of heterogeneous parameter maps for testing of spatially heterogeneous parameter maps: Application to dynamic contrast‐enhanced MRI biomarkers. Magn. Reson. Med. 71, 1299-1311, (2014). doi: 10.1002/mrm.24755

I. Teh, F.-L. Zhou, P.L. Hubbard Cristinacce, G.J.M. Parker, J.E. Schneider. Biomimetic phantom for cardiac diffusion MRI. J Magn. Reson. Imag. 43(3), 594-600, (2016). doi: 10.1002/jmri.25014, Front cover


Other

C. Roberts, G.J.M. Parker, C. Rose, Y. Watson, J.P. O’Connor, S. Stivaros, A. Jackson, V.E. Rushton. The use of DCE-MRI and tracer kinetic modeling in the assessment of glandular function in Sjögren's syndrome. Radiology 246, 845-853, (2008).

L.E. Kershaw, J.H. Naish,D.M. McGrath, J.C. Waterton, G.J.M. Parker. Measurement of arterial plasma oxygenation in dynamic oxygen-enhanced MRI. Magnetic Resonance in Medicine, 64(6), 1838–1842, (2010). doi:10.1002/mrm.22571

I. Huen, D.M. Morris, C. Wright, G.J.M. Parker, C.P. Sibley, E.D. Johnstone, J.H. Naish. R1 and R2* changes in the human placenta in response to maternal oxygen challenge. Magn. Reson. Med. 70(5), 1427-1433, (2013). doi: 10.1002/mrm.24581

C.A. Miller, J.H. Naish, P. Bishop, G. Coutts, D. Clark, S. Zhao, S.G. Ray, N. Yonan, S.G. Williams, A.S. Flett, J.C. Moon, A. Greiser, G.J.M. Parker, M. Schmitt. Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume. Circulation Cardiovasc. Imag. 6, 373-383, (2013). doi: 10.1161/CIRCIMAGING.112.000192

J.L. Ulloa, S. Stahl, J. Yates, N. Woodhouse, J.G. Kenna, H.B. Jones, J.C. Waterton, P.D. Hockings. Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition. NMR Biomed. 26(10), 1258–1270, (2013). doi: 10.1002/nbm.2946

C.A. Miller, J. Sarma, J.H. Naish, N. Yonan, S.G. Williams, S.M. Shaw, D. Clark, K. Pearce, M. Stout, R. Potluri, A. Borg, G. Coutts, S. Chowdhary, G.P. McCann, G.J.M. Parker, S.G. Ray, M. Schmitt. Multiparametric cardiovascular magnetic resonance assessment of cardiac allograft vasculopathy. J. Amer. Coll. Cardiol. 63(8), 799-808, (2014).

G.J.M. Parker. Seeing within: Magnetic resonance imaging in drug development. Drug Discovery World, Winter 2015/16, 19-22, (2016).

J.C. Waterton, M. Ho, L.H. Nordenmark, M. Jenkins, J. DiCarlo, G. Guillard, C. Roberts, G. Buonaccorsi, G.J.M. Parker, M.A. Bowes, C. Peterfy, H. Kellner, P.C. Taylor. Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting. European Radiology. (In press) http://doi.org/10.1007/s00330-017-4736-9 


Selected conference publications

D. McGrath, J.H. Naish, A. Lacey, C.J. Taylor, G.J. Parker. A Compartmental Model for Oxygen-Enhanced Magnetic Resonance Imaging of the Lung. Proc. ISMRM 15th meeting, Berlin, (2007).

K.V. Embleton, H. Haroon, D.M. Morris, M. Lambon-Ralph, G.J. Parker. Anatomical connectivity mapping. Proc. ISMRM 15th meeting, Berlin, (2007).

J.H. Naish, D.M. McGrath, C.E. Hutchinson, L.E. Olsson, J.C. Waterton, C.J. Taylor, G.J. Parker. Increased Pulmonary Capillary Permeability in Smokers as Measured by DCE-MRI. Proc. ISMRM 16th meeting, Toronto, 401, (2008).

D.M. McGrath, J. Naish, C. Taylor, C Hutchinson, G. Parker. Method for Correction of Breathing-Dependent Signal Changes in Dynamic Lung Oxygen-Enhanced MRI – Improved Sensitivity in Smokers. Proc. ISMRM 16th meeting, Toronto, 2641, (2008).

D.M. McGrath, J.H. Naish, S.S. Young, L.E. Olsson, C.E. Hutchinson, J. Vestbo, J.C. Waterton, C.J. Taylor, G.J. Parker. Compartmental Model Analysis of Oxygen-Enhanced MRI and DCE-MRI Detects Pre-morbid Lung Damage in Smokers. Proc. ISMRM 17th meeting, Honolulu, 2016, (2009).

P.L. Hubbard, G.J. Parker, D. Singh, J. Vestbo, S.S. Young, E. Bondesson, L.E. Olsson, J.H. Naish. A new approach to ventilation-perfusion mapping – oxygen-enhanced magnetic resonance imaging in chronic obstructive pulmonary disease. Proc. American Thoracic Society, New Orleans, A6625, (2010).

P.L. Hubbard, G.J. Parker, D. Singh, J. Vestbo, S.S. Young, E. Bondesson, L.E. Olsson, J.H. Naish. Mapping the ventilation–perfusion ratio in chronic obstructive pulmonary disease using oxygen-enhanced MRI. Proc. ISMRM 18th meeting, Stockholm, 2515, (2010).

J.H. Naish, G.J. Parker. Physiological modelling of oxygen-enhanced MRI in the lung. Proc. ISMRM 18th meeting, Stockholm, 2516, (2010).

M. Bozzali, G. Parker, L. Serra, R. Perri, F. Giubilei, C. Marra, C. Caltagirone, M. Cercignani. Anatomical connectivity to assess brain tissue modifications in Alzheimer’s disease. Proc. ISMRM 19th meeting, Montreal, 683, (2011).

C.J. Rose, P.L. Hubbard, C. Roberts, S.S. Young, J.H. Naish, G.J. Parker. Physiological Modelling of Dynamic Oxygen-Enhanced MRI in the Lung: Model Fitting and Parameter Interpretation. Proc. ISMRM 19th meeting, Montreal, 928, (2011).

I.V. Linnik, M. Scott, N. Woodhouse, J.C. Waterton, H. Young, C. Liess, H. Barjat, J. Ulloa, C.L. Hodgkinson, T. Ward, C. Dive, D. Roberts, J.H. Naish, G.J. Parker. Histological Verification of Oxygen-Enhanced MRI for Detection of Hypoxia. Proc. ISMRM 19th meeting, Montreal, 554, (2011).

K.F. Holliday, G. Thompson, S.J. Mills, G. Buonaccorsi, A. Jackson, J.H. Naish, G.J. Parker. Demonstration of the relationship between oxygen delivery and contrast agent delivery in human glioma using combined OEMRI and DCE-MRI. Proc. ISMRM 19th meeting, Montreal, 2426, (2011).

P.L. Hubbard, G.J. Parker, D. Singh, E. Bondesson, L.E. Olsson, L. Wigström, S.S. Young, J.H. Naish. Heterogeneity of the ventilation–perfusion ratio in lung disease using OE-MRI. Proc. ISMRM 19th meeting, Montreal, 542, (2011).

P.L. Hubbard, G.J.M. Parker, D. Singh, J. Vestbo, E. Bondesson, L.E. Olsson, L. Wigström, S.S. Young, J.H. Naish. Novel ventilation-perfusion ratio measurements in COPD using MRI. Proc. European Respiratory Society Congress, Amsterdam, 1880, (2011).

W. Zhang, P. Hubbard, E. Bondesson, L. Wigström, S. Young, D. Singh, G. Parker, J. Naish. Ventilation-perfusion mismatch in COPD with or without emphysema: comparison of structural CT and functional OE-MRI. Proc. European Respiratory Society Congress, Amsterdam, 1882, (2011).

M. Lyksborg, R. Larsen, P.S. Sørensen, M. Blinkenberg, A. Dogonowski, E. Garde, G.J.M. Parker, H.R. Siebner, T.B. Dyrby. Anatomical Connectivity Mapping – Measuring connectivity changes in multiple sclerosis. Proc. ISMRM 20th meeting, Melbourne, 501, (2012).

C.J. Rose, P.L. Hubbard, T.F. Cootes, C.J. Taylor, J.H. Naish, G.J. Parker, S.S. Young, J.C. Waterton. Are two samples of parametric images statistically different? Novel significance tests on samples of density estimates, with application to ventilation-to-perfusion mapping of the lung in COPD using oxygen-enhanced MRI. Proc. ISMRM 20th meeting, Melbourne, 755, (2012).

A.R. Morgan, A. Ali, P.L. Hubbard, G.J.M. Parker, M.L.J. Scott, S.S. Young, L.E. Olsson, C. Roberts, J.H. Naish. Effect of image registration on oxygen-enhanced MRI of the lung. Proc. ISMRM 20th meeting, Melbourne, 1336, (2012).

W. Zhang, P.L. Hubbard, E. Bondesson, L. Wigström, S.S. Young, D. Singh, G.J.M. Parker, J.H. Naish. Ventilation-perfusion mismatch in COPD with or without emphysema: comparison of functional OE-MRI and structural CT. Proc. ISMRM 20th meeting, Melbourne, 1345, (2012).

B. Spano, M. Cercignani, G.J.M. Parker, M. Castelli, B. Basile, S. Rossi, L. Serra, G. Magnani, U. Nocentini, C. Caltagirone, D. Centonze, M. Bozzali. Anatomical brain connectivity to assess cognitive dysfunction in MS. Proc. ISMRM 20th meeting, Melbourne, 3126, (2012).

W. Zhang, R.M. Niven, S.S Young, Y. Liu, P.L. Hubbard, G.J.M. Parker, J.H. Naish. Dynamic OE-MRI of the lung in asthma: preliminary findings. Proc. American Thoracic Society, Philadelphia, (2013).

A.R. Morgan, G.J.M. Parker, P.L. Hubbard, W. Zhang, D. Singh, J. Vestbo, S.S. Young, L.H. Nordenmark, M.L.J. Scott, J.H. Naish. Pulmonary strain and compliance mapping in COPD: Investigating reproducibility and correlation with CT and spirometry. Proc. American Thoracic Society, Philadelphia, (2013).

A.R Morgan, G.J.M. Parker, C. Roberts, N. Maguire, G.A. Buonaccorsi, P.L. Hubbard, D. Singh, J. Vestbo, L. Bjermer, J. Jögi, L.H. Nordenmark, Z. Taib, J. Sarv, P. Bruijnzeel, J.C. Waterton. Evaluating dynamic oxygen-enhanced MRI biomarkers of lung function: Sensitivity to conventional COPD treatment. Proc. European Respiratory Society Congress, Barcelona. Eur. Respir. J. 42 Supl 57, P2268, (2013).

W. Zhang, R.M. Niven, S.S. Young, Y. Liu, P.L. Hubbard, G.J.M. Parker, J.H. Naish. Pulmonary response to salbutamol inhalation using dynamic OE-MRI in patients with asthma. Proc. European Respiratory Society Congress, Barcelona. Eur. Respir. J. 42 Supl 57, 3028, (2013).

W. Zhang, R.M. Niven, S.S. Young, Y. Liu, P.L. Hubbard, G.J.M. Parker, J.H. Naish. Dynamic OE-MRI of the lung in asthma. Proc. ISMRM 21st meeting, Salt Lake City, 648, (2013).

A.R. Morgan, G.J.M. Parker, M.L.J. Scott, J.H. Naish. 3D Strain Mapping in the Lung. Proc. ISMRM 21st meeting, Salt Lake City, 1485, (2013).

J. Ulloa, A. Morgan, G. Parker. Evaluation of whole lung 3D dynamic oxygen-enhanced MRI. Proc. European Respiratory Society Congress, Munich. Eur Respir. J. 44 Suppl 58, 1724 (2014).

W.-J. Zhang, R. Niven, S. Young, Y.-Z. Liu, G. Parker, J. Naish. Quantitative dynamic contrast-enhanced MRI of the lung in asthma. Proc. European Respiratory Society Congress, Munich. Eur Respir. J. 44 Suppl 58, 1726 (2014).

J.L. Ulloa, A.R. Morgan, G.J. Parker. Whole Lung 3D Dynamic Oxygen-Enhanced MRI Protocol. Proc. ATS, San Diego. Am J Respir Crit Care Med 189, A6692, (2014).

J.P.B. O'Connor, Y. Jamin, J.K.R. Boult, M. Babur, J.C. Waterton, D. McHugh, A.R. Reynolds, K.J. Williams, G.J.M. Parker, S.P. Robinson. Multiparametric MRI mapping of oxygen delivery and hypoxia in renal 786-O-R murine xenografts. Proc. Intl. Soc. Mag. Reson. Med. 22, Milan, 46, (2014).

M.F. Forsgren, J.L. Ulloa, P.D. Hockings. Simplified model for Gd-EOB-DTPA DCE-MRI liver function analysis. Proc. Intl. Soc. Mag. Reson. Med. 22, Milan, 522, (2014).

J.L Ulloa, W. Zhang, J. Naish, A.R Morgan, G.J.M. Parker. Population-based parameterization of the oxygen input function (OIF) for dynamic oxygen-enhanced MRI. Proc. Intl. Soc. Mag. Reson. Med. 22, Milan, 3547, (2014).

J. Tabernero, G. Parker, A. Clamp, E. Elez, N. Mescallado, R. Dienstmann, T. Sauri, J. Hasan, J.J Mateos, R. Bruns, C. Gimmi, G.C. Jayson. Investigation of the anti-angiogenic effects of abituzumab in patients with colorectal or ovarian cancer and liver metastases using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Proc. AACR-NCI-EORTC International Conference, Boston, C119, (2015).

J.L. Ulloa, A.R. Morgan, T. Lacey, C. Roberts, G.J.M. Parker. V/Q scanning using oxygen-enhanced Magnetic Resonance Imaging. Proc. British Thoracic Society Winter Meeting, London. Thorax 70 Suppl 3, A221 (2015) doi:10.1136/thoraxjnl-2015-207770.420

C. Roberts, G. Guillard, M.A. Bowes, R. O’Connor, N. Maguire, A. Morgan, G.J. Parker, R. Hodgson, E.M. Vital, P. Bird, G.R. Vincent, P. Emery, P.G. Conaghan. A Novel, Fully 3-Dimensional Dynamic Contrast MRI Method in the Hand Reveals Details of Synovial Inflammation and Provides a Sensitive Measure of Change. Proc. EULAR, Rome, SAT0601. Ann Rheum Dis 74, 879 doi:10.1136/annrheumdis-2015-eular.6400

J.L. Ulloa, A.R. Morgan, G.J.M. Parker. Evaluation of a novel whole lung 3D dynamic OE-MRI protocol in healthy subjects. Proc. Intl. Soc. Mag. Reson. Med. 23, 3973, (2015).

C.B. Whitley, M.L. Escolar, S. Vijay, G. Parker, M. Leavitt, A. Rossomando, X. Zhang, A. Cinar, K.C. Patki, S. Rojas-Caro. Initial, 24-Week Results of Heparan Sulfate Levels in Cerebrospinal Fluid and Serum, Brain Structural MRI, and Neurocognitive Evaluations in a Phase 1/2, First-in-Human Clinical Trial of Intravenous SBC-103 in Mucopolysaccharidosis IIIB. Proc. 14th International Symposium on MPS and Related Diseases, July 14–17, 2016, Bonn, Germany.

K. Martini, C. Benden, G. Parker, S. Baumüller, J. Ulloa, A. Morgan, T. Frauenfelder. Oxygen-enhanced MR (OE-MR): Correlation to CT Brody score in cystic fibrosis patients. Proc. Eur. Resp. Soc. (2016). doi: 10.1183/13993003.congress-2016.OA1492