New Bioxydyn publications show the power of lung MRI

26 Jan 2015

Bioxydyn has been involved in a cluster of groundbreaking research papers that demonstrate the power of lung MRI in COPD and asthma. The research exploits two of Bioxydyn's tecnologies - oxygen-enhanced MRI (OE-MRI) and MRI for tissue density measurement (qS0). The COPD work shows that dynamic OE-MRI is sensitive to the disease and to the effects of anti-inflammatory treatment and that qS0 measurements provide equivalent information to CT for the measurement of lung density. The asthma work also shows that dynamic OE-MRI is sensitive to the severity of disease.  These findings show the power and versitility of MRI for characterising lung structure and function in disease using safe, repeatable and accessible technology.

Publication details

A.R. Morgan, G.J.M. Parker, C. Roberts, G.A. Buonaccorsi, N.C. Maguire, P.L. Hubbard Cristinacce, D. Singh, J. Vestbo, L. Bjermer, J. Jögli, Z. Taib, J. Sarv, P.L.B. Bruijnzeel, L.E. Olsson, E. Bondesson, U. Nihlen, D.M. McGrath, S.S. Young, J.C. Waterton, L.H. Nordenmark. Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD. Eur. J. Radiol. 38, 2093-2101, (2014). doi: 10.1016/j.ejrad.2014.08.004

W.-J. Zhang, R.M. Niven, S.S. Young, Y.-Z. Liud, G.J.M. Parker, J.H. Naish. Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma—Initial experience. Eur. J. Radiol. 84(2), 318-326, (2015). doi: 10.1016/j.ejrad.2014.10.021.

W.-J. Zhang, P.L. Hubbard Cristinacce, E. Bondesson, L.H. Nordenmark, S.S. Young, Y.-Z. Liu, D. Singh, J.H. Naish, G.J.M. Parker. MR quantitative equilibrium signal mapping: a reliable alternative to CT for the assessment of emphysema in COPD. Radiology (In press). 10.1148/radiol.14132953



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