Quantifying lung density in COPD using MRI - an alternative to CT?
11 May 2015
We are proud to have been involved in the generation of a recent paper in the journal Radiology that describes the use of quantitative MRI methods to characterise lung density changes in COPD. The paper, which involved collaborative between the University of Manchester and AstraZeneca, shows that the information on lung density that can be provided using MRI is equivalent to that available from CT, but without the ionising radiation burden. In addition to the suggested utility of the method in characterising tissue loss in COPD, it is likely that MRI quantification of lung density changes may in the future also play a role in charaterising density alterations due to fibrosis and inflammation.
Full citation information: W.-J. Zhang, P.L. Hubbard Cristinacce, E. Bondesson, L.H. Nordenmark, S.S. Young, Y.-Z. Liu, D. Singh, J.H. Naish, G.J.M. Parker. MR quantitative equilibrium signal mapping: a reliable alternative to CT for the assessment of emphysema in COPD. Radiology. 275(2), 579-588, (2015). doi: 10.1148/radiol.14132953